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Caspase-8: A Novel Target to Overcome Resistance to Chemotherapy in Glioblastoma

Caspase-8 was originally identified as a central player of programmed cell death triggered by death receptor stimulation. In that context, its activity is tightly regulated through several mechanisms, with the best established being the expression of FLICE-like inhibitory protein (FLIP) family prote...

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Detalles Bibliográficos
Autores principales: Fianco, Giulia, Contadini, Claudia, Ferri, Alessandra, Cirotti, Claudia, Stagni, Venturina, Barilà, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320982/
https://www.ncbi.nlm.nih.gov/pubmed/30501030
http://dx.doi.org/10.3390/ijms19123798