In-Line UV-Vis Spectroscopy as a Fast-Working Process Analytical Technology (PAT) during Early Phase Product Development Using Hot Melt Extrusion (HME)

This paper displays the potential of an in-line PAT system for early phase product development during pharmaceutical continuous manufacturing following a Quality by Design (QbD) framework. Hot melt extrusion (HME) is used as continuous manufacturing process and UV–Vis spectroscopy as an in-line moni...

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Detalles Bibliográficos
Autores principales: Schlindwein, Walkiria, Bezerra, Mariana, Almeida, Juan, Berghaus, Andreas, Owen, Martin, Muirhead, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321000/
https://www.ncbi.nlm.nih.gov/pubmed/30249025
http://dx.doi.org/10.3390/pharmaceutics10040166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321000/
https://www.ncbi.nlm.nih.gov/pubmed/30249025
http://dx.doi.org/10.3390/pharmaceutics10040166

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