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Interaction of Arylidenechromanone/Flavanone Derivatives with Biological Macromolecules Studied as Human Serum Albumin Binding, Cytotoxic Effect, Biocompatibility Towards Red Blood Cells

The aim of this study was to determine the cytotoxic effect of 3-arylidenechromanone (1) and 3-arylideneflavanone (2) on HL-60 and NALM-6 cell lines (two human leukemia cell lines) and a WM-115 melanoma cell line. Both compounds exhibited high cytotoxic activity with higher cytotoxicity exerted by c...

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Detalles Bibliográficos
Autores principales: Adamus-Grabicka, Angelika A., Markowicz-Piasecka, Magdalena, Ponczek, Michał B., Kusz, Joachim, Małecka, Magdalena, Krajewska, Urszula, Budzisz, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321038/
https://www.ncbi.nlm.nih.gov/pubmed/30513785
http://dx.doi.org/10.3390/molecules23123172