Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation

A variety of cellular stresses lead to global translation attenuation due to phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2), which decreases the availability of the eIF2-GTP-Met-tRNA(i) ternary complex. However, a subset of mRNAs continues to be translated by non-canon...

Descripción completa

Detalles Bibliográficos
Autores principales: Ross, Joseph A., Bressler, Kamiko R., Thakor, Nehal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321046/
https://www.ncbi.nlm.nih.gov/pubmed/30551605
http://dx.doi.org/10.3390/ijms19124032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321046/
https://www.ncbi.nlm.nih.gov/pubmed/30551605
http://dx.doi.org/10.3390/ijms19124032

Ejemplares similares