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Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation

A variety of cellular stresses lead to global translation attenuation due to phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2), which decreases the availability of the eIF2-GTP-Met-tRNA(i) ternary complex. However, a subset of mRNAs continues to be translated by non-canon...

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Detalles Bibliográficos
Autores principales:	Ross, Joseph A., Bressler, Kamiko R., Thakor, Nehal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321046/ https://www.ncbi.nlm.nih.gov/pubmed/30551605 http://dx.doi.org/10.3390/ijms19124032

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