Complementary Quantitative Structure–Activity Relationship Models for the Antitrypanosomal Activity of Sesquiterpene Lactones

Three complementary quantitative structure–activity relationship (QSAR) methodologies, namely, regression modeling based on (i) “classical” molecular descriptors, (ii) 3D pharmacophore features, and (iii) 2D molecular holograms (HQSAR) were employed on the antitrypanosomal activity of sesquiterpene...

Descripción completa

Detalles Bibliográficos
Autores principales: Kimani, Njogu M., Matasyoh, Josphat C., Kaiser, Marcel, Nogueira, Mauro S., Trossini, Gustavo H. G., Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321053/
https://www.ncbi.nlm.nih.gov/pubmed/30467296
http://dx.doi.org/10.3390/ijms19123721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321053/
https://www.ncbi.nlm.nih.gov/pubmed/30467296
http://dx.doi.org/10.3390/ijms19123721

Ejemplares similares