23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells

The natural product 23-hydroxyursolic acid (23-HUA) is a derivative of ursolic acid, which is known to induce cancer cell apoptosis. However, apoptotic effects and mechanisms of 23-HUA have not been well characterized yet. Herein, we investigated the molecular mechanisms of 23-HUA-induced apoptosis...

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Detalles Bibliográficos
Autores principales: Won, Jong-Heon, Chung, Kyung-Sook, Park, Eun-Young, Lee, Jeong-Hun, Choi, Jung-Hye, Tapondjou, Leon Azefack, Park, Hee-Juhn, Nomura, Masaaki, Hassan, Ahmed H.E., Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321063/
https://www.ncbi.nlm.nih.gov/pubmed/30551620
http://dx.doi.org/10.3390/molecules23123306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321063/
https://www.ncbi.nlm.nih.gov/pubmed/30551620
http://dx.doi.org/10.3390/molecules23123306

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