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Copper-Promoted Cross-Coupling Reactions for the Synthesis of Aryl(difluoromethyl)phosphonates Using Trimethylsilyl(difluoromethyl)phosphonate

A convenient and effective route for the synthesis of aryl(difluoromethyl)phosphonates has been developed based on cross-coupling reactions. Upon treatment with a stoichiometric amount (or a catalytic amount in some cases) of CuI and CsF, aryl iodides reacted smoothly with (silyldifluoromethyl)phosp...

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Detalles Bibliográficos
Autores principales: Komoda, Kazuki, Iwamoto, Rei, Kasumi, Masakazu, Amii, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321065/
https://www.ncbi.nlm.nih.gov/pubmed/30545029
http://dx.doi.org/10.3390/molecules23123292