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Topical Application of JAK1/JAK2 Inhibitor Momelotinib Exhibits Significant Anti-Inflammatory Responses in DNCB-Induced Atopic Dermatitis Model Mice

Atopic dermatitis (AD) is a chronic recurrent skin disease dominated by T-helper 2 inflammation. Momelotinib (MMB) is a novel JAK1/JAK2 inhibitor suppressing the signal transduction of multiple pro-inflammatory cytokines. Recent studies indicated that JAK inhibitor could play a therapeutic role in A...

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Detalles Bibliográficos
Autores principales: Jin, Wenyu, Huang, Wei, Chen, Liqing, Jin, Mingji, Wang, Qiming, Gao, Zhonggao, Jin, Zhehu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321094/
https://www.ncbi.nlm.nih.gov/pubmed/30544712
http://dx.doi.org/10.3390/ijms19123973