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Topical Application of JAK1/JAK2 Inhibitor Momelotinib Exhibits Significant Anti-Inflammatory Responses in DNCB-Induced Atopic Dermatitis Model Mice
Atopic dermatitis (AD) is a chronic recurrent skin disease dominated by T-helper 2 inflammation. Momelotinib (MMB) is a novel JAK1/JAK2 inhibitor suppressing the signal transduction of multiple pro-inflammatory cytokines. Recent studies indicated that JAK inhibitor could play a therapeutic role in A...
Autores principales: | Jin, Wenyu, Huang, Wei, Chen, Liqing, Jin, Mingji, Wang, Qiming, Gao, Zhonggao, Jin, Zhehu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321094/ https://www.ncbi.nlm.nih.gov/pubmed/30544712 http://dx.doi.org/10.3390/ijms19123973 |
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