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Insight into Inhibitor Binding in the Eukaryotic Proteasome: Computations of the 20S CP
A combination of molecular dynamics (MD) simulations and computational analyses uncovers structural features that may influence substrate passage and exposure to the active sites within the proteolytic chamber of the 20S proteasome core particle (CP). MD simulations of the CP reveal relaxation dynam...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321098/ https://www.ncbi.nlm.nih.gov/pubmed/30514002 http://dx.doi.org/10.3390/ijms19123858 |