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α-Melanocyte-Stimulating Hormone Attenuates Neovascularization by Inducing Nitric Oxide Deficiency via MC-Rs/PKA/NF-κB Signaling

α-melanocyte-stimulating hormone (α-MSH) has been characterized as a novel angiogenesis inhibitor. The homeostasis of nitric oxide (NO) plays an important role in neovascularization. However, it remains unclear whether α-MSH mitigates angiogenesis through modulation of NO and its signaling pathway....

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Detalles Bibliográficos
Autores principales: Weng, Wen-Tsan, Wu, Chieh-Shan, Wang, Feng-Sheng, Wu, Chang-Yi, Ma, Yi-Ling, Chan, Hoi-Hung, Wu, Den-Chiung, Wu, Jian-Ching, Chu, Tian-Huei, Huang, Shih-Chung, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321109/
https://www.ncbi.nlm.nih.gov/pubmed/30513637
http://dx.doi.org/10.3390/ijms19123823