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α-Melanocyte-Stimulating Hormone Attenuates Neovascularization by Inducing Nitric Oxide Deficiency via MC-Rs/PKA/NF-κB Signaling
α-melanocyte-stimulating hormone (α-MSH) has been characterized as a novel angiogenesis inhibitor. The homeostasis of nitric oxide (NO) plays an important role in neovascularization. However, it remains unclear whether α-MSH mitigates angiogenesis through modulation of NO and its signaling pathway....
Autores principales: | Weng, Wen-Tsan, Wu, Chieh-Shan, Wang, Feng-Sheng, Wu, Chang-Yi, Ma, Yi-Ling, Chan, Hoi-Hung, Wu, Den-Chiung, Wu, Jian-Ching, Chu, Tian-Huei, Huang, Shih-Chung, Tai, Ming-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321109/ https://www.ncbi.nlm.nih.gov/pubmed/30513637 http://dx.doi.org/10.3390/ijms19123823 |
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