Modular Synthesis and Biological Investigation of 5-Hydroxymethyl Dibenzyl Butyrolactones and Related Lignans

Dibenzyl butyrolactone lignans are well known for their excellent biological properties, particularly for their notable anti-proliferative activities. Herein we report a novel, efficient, convergent synthesis of dibenzyl butyrolactone lignans utilizing the acyl-Claisen rearrangement to stereoselecti...

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Detalles Bibliográficos
Autores principales: Davidson, Samuel J., Pilkington, Lisa I., Dempsey-Hibbert, Nina C., El-Mohtadi, Mohamed, Tang, Shiying, Wainwright, Thomas, Whitehead, Kathryn A., Barker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321111/
https://www.ncbi.nlm.nih.gov/pubmed/30467285
http://dx.doi.org/10.3390/molecules23123057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321111/
https://www.ncbi.nlm.nih.gov/pubmed/30467285
http://dx.doi.org/10.3390/molecules23123057

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