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Studies on the Dual Activity of EGFR and HER-2 Inhibitors Using Structure-Based Drug Design Techniques

HER-2 and EGFR are biological targets related to the development of cancer and the discovery and/or development of a dual inhibitor could be a good strategy to design an effective drug candidate. In this study, analyses of the chemical properties of a group of substances having affinity for both HER...

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Detalles Bibliográficos
Autores principales: de Angelo, Rafaela Molina, Almeida, Michell de Oliveira, de Paula, Heberth, Honorio, Kathia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321113/
https://www.ncbi.nlm.nih.gov/pubmed/30477154
http://dx.doi.org/10.3390/ijms19123728