A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

An in silico study has been conducted upon (3′RS,5′SR)-5-[2′-benzyl-5′-hydroxymethyl-1′,2′-isoxazolidin-3′-yl]uracil through a molecular dynamics/docking approach that highlights its potential inhibitory activity upon the wild-type pseudouridine 5′-monophosphate glycosidase. The crystal structure of...

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Detalles Bibliográficos
Autores principales: Floresta, Giuseppe, Pistarà, Venerando, Christensen, Kirsten E., Amata, Emanuele, Marrazzo, Agostino, Gentile, Davide, Rescifina, Antonio, Punzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321120/
https://www.ncbi.nlm.nih.gov/pubmed/30572684
http://dx.doi.org/10.3390/molecules23123381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321120/
https://www.ncbi.nlm.nih.gov/pubmed/30572684
http://dx.doi.org/10.3390/molecules23123381

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