Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53

Tumor development and progression is the consequence of genetic as well as epigenetic alterations of the cell. As part of the epigenetic regulatory system, histone acetyltransferases (HATs) and deacetylases (HDACs) drive the modification of histone as well as non-histone proteins. Derailed acetylati...

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Detalles Bibliográficos
Autores principales: Mrakovcic, Maria, Bohner, Lauren, Hanisch, Marcel, Fröhlich, Leopold F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321134/
https://www.ncbi.nlm.nih.gov/pubmed/30544838
http://dx.doi.org/10.3390/ijms19123952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321134/
https://www.ncbi.nlm.nih.gov/pubmed/30544838
http://dx.doi.org/10.3390/ijms19123952

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