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Development of Paroxetine Hydrochloride Single Layer Controlled-Release Tablets Based on 3(2) Factorial Design

Major depressive disorder (MDD) is one of the main contributors to disability and suicide mortality globally. Paroxetine hydrochloride (PHH) is the most potent antidepressant used for MDD treatment. Due to its reduced side effects PAXIL(®) CR is a widely-used controlled-release formulation of PHH. H...

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Detalles Bibliográficos
Autores principales: Yang, Yao, Huang, Zhengwei, Zhang, Xuan, Li, Jinyuan, Huang, Ying, Chen, Wanxin, Pan, Xin, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321141/
https://www.ncbi.nlm.nih.gov/pubmed/30463329
http://dx.doi.org/10.3390/pharmaceutics10040243