A Novel Synthetic Dihydroindeno[1,2-b] Indole Derivative (LS-2-3j) Reverses ABCB1- and ABCG2-Mediated Multidrug Resistance in Cancer Cells

10-oxo-5-(3-(pyrrolidin-1-yl) propyl)-5,10-dihydroindeno [1,2-b] indol-9-yl propionate (LS-2-3j) is a new chemically synthesized indole compound and some related analogues are known to be inhibitors (such as alectinib and Ko143) of ATP-binding cassette (ABC) transporters, especially the ABC transpor...

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Detalles Bibliográficos
Autores principales: Guo, Chao, Liu, Fangyuan, Qi, Jie, Ma, Jiahui, Lin, Shiqi, Zhang, Caiyun, Zhang, Qian, Zhang, Hangyu, Lu, Rong, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321174/
https://www.ncbi.nlm.nih.gov/pubmed/30544754
http://dx.doi.org/10.3390/molecules23123264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321174/
https://www.ncbi.nlm.nih.gov/pubmed/30544754
http://dx.doi.org/10.3390/molecules23123264

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