Cargando…

Dysregulation of Lipid Metabolism in Mkp-1 Deficient Mice during Gram-Negative Sepsis

Mitogen-activated protein kinase phosphatase (Mkp)-1 exerts its anti-inflammatory activities during Gram-negative sepsis by deactivating p38 and c-Jun N-terminal kinase (JNK). We have previously shown that Mkp-1(+/+) mice, but not Mkp-1(−/−) mice, exhibit hypertriglyceridemia during severe sepsis. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jinhui, Wang, Xiantao, Ackerman, William E., Batty, Abel J., Kirk, Sean G., White, William M., Wang, Xianxi, Anastasakis, Dimitrios, Samavati, Lobelia, Buhimschi, Irina, Nelin, Leif D., Hafner, Markus, Liu, Yusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321205/
https://www.ncbi.nlm.nih.gov/pubmed/30563203
http://dx.doi.org/10.3390/ijms19123904