RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics

Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence of accessible double-stranded RNA structures based on sequencing of...

Descripción completa

Detalles Bibliográficos
Autores principales: Bindewald, Eckart, Dai, Lisheng, Kasprzak, Wojciech K., Kim, Taejin, Gu, Shuo, Shapiro, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321275/
https://www.ncbi.nlm.nih.gov/pubmed/30558267
http://dx.doi.org/10.3390/molecules23123329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321275/
https://www.ncbi.nlm.nih.gov/pubmed/30558267
http://dx.doi.org/10.3390/molecules23123329

Ejemplares similares