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RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics

Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence of accessible double-stranded RNA structures based on sequencing of...

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Detalles Bibliográficos
Autores principales:	Bindewald, Eckart, Dai, Lisheng, Kasprzak, Wojciech K., Kim, Taejin, Gu, Shuo, Shapiro, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321275/ https://www.ncbi.nlm.nih.gov/pubmed/30558267 http://dx.doi.org/10.3390/molecules23123329

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