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CRISPR/Cas9-Mediated Deletion of Large Genomic Fragments in Soybean

At present, the application of CRISPR/Cas9 in soybean (Glycine max (L.) Merr.) has been mainly focused on knocking out target genes, and most site-directed mutagenesis has occurred at single cleavage sites and resulted in short deletions and/or insertions. However, the use of multiple guide RNAs for...

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Detalles Bibliográficos
Autores principales: Cai, Yupeng, Chen, Li, Sun, Shi, Wu, Cunxiang, Yao, Weiwei, Jiang, Bingjun, Han, Tianfu, Hou, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321276/
https://www.ncbi.nlm.nih.gov/pubmed/30513774
http://dx.doi.org/10.3390/ijms19123835