DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines

A mild and highly efficient metal-free oxidative α-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-Bu)(3)SnCN. Employing readily removable N-acyl/sul...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hong Pyo, Yu, Heesun, Kim, Hyoungsu, Kim, Seok-Ho, Lee, Dongjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321290/
https://www.ncbi.nlm.nih.gov/pubmed/30563272
http://dx.doi.org/10.3390/molecules23123223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321290/
https://www.ncbi.nlm.nih.gov/pubmed/30563272
http://dx.doi.org/10.3390/molecules23123223

Ejemplares similares