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DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines

A mild and highly efficient metal-free oxidative α-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-Bu)(3)SnCN. Employing readily removable N-acyl/sul...

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Detalles Bibliográficos
Autores principales:	Kim, Hong Pyo, Yu, Heesun, Kim, Hyoungsu, Kim, Seok-Ho, Lee, Dongjoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321290/ https://www.ncbi.nlm.nih.gov/pubmed/30563272 http://dx.doi.org/10.3390/molecules23123223

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