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Flux-Independent NMDAR Signaling: Molecular Mediators, Cellular Functions, and Complexities
The glutamate (Glu) N-methyl-d-aspartate (NMDA) receptor (NMDAR) plays a critical role in synaptic communication given mainly by its ionotropic function that permeates Ca(2+). This in turn activates calmodulin that triggers CaMKII, MAPK, CREB, and PI3K pathways, among others. However, NMDAR signalin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321296/ https://www.ncbi.nlm.nih.gov/pubmed/30501045 http://dx.doi.org/10.3390/ijms19123800 |