The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization

The search for novel anticancer small molecules and strategies remains a challenge. Our previous studies have identified TXA1 (1-{[2-(diethylamino)ethyl]amino}-4-propoxy-9H- thioxanthen-9-one) as a hit compound, with in vitro antitumor potential by modulating autophagy and apoptosis in human tumor c...

Descripción completa

Detalles Bibliográficos
Autores principales: Lima, Raquel T., Sousa, Diana, Gomes, Ana Sara, Mendes, Nuno, Matthiesen, Rune, Pedro, Madalena, Marques, Franklim, Pinto, Madalena M., Sousa, Emília, Vasconcelos, M. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321308/
https://www.ncbi.nlm.nih.gov/pubmed/30545153
http://dx.doi.org/10.3390/molecules23123301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321308/
https://www.ncbi.nlm.nih.gov/pubmed/30545153
http://dx.doi.org/10.3390/molecules23123301

Ejemplares similares