A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase

Protein kinase B (Akt) is a key enzyme in the insulin signalling cascade, required for insulin-stimulated NO production in endothelial cells (ECs). Previous studies have suggested that AMP-activated protein kinase (AMPK) activation stimulates NO synthesis and enhances insulin-stimulated Akt activati...

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Detalles Bibliográficos
Autores principales: Strembitska, Anastasiya, Mancini, Sarah J., Gamwell, Jonathan M., Palmer, Timothy M., Baillie, George S., Salt, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321332/
https://www.ncbi.nlm.nih.gov/pubmed/30563079
http://dx.doi.org/10.3390/ijms19123886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321332/
https://www.ncbi.nlm.nih.gov/pubmed/30563079
http://dx.doi.org/10.3390/ijms19123886

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