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HFIP-Promoted Bischler Indole Synthesis under Microwave Irradiation

1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transformed into indole derivatives with moderate t...

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Detalles Bibliográficos
Autores principales: Yao, Guangkai, Zhang, Zhi-Xiang, Zhang, Cheng-Bei, Xu, Han-Hong, Tang, Ri-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321335/
https://www.ncbi.nlm.nih.gov/pubmed/30558133
http://dx.doi.org/10.3390/molecules23123317