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Construction of Novel Aspartokinase Mutant A380I and Its Characterization by Molecular Dynamics Simulation

In this study, a novel monomer aspartokinase (AK) from Corynebacterium pekinense was identified, and its monomer model was constructed. Site 380 was identified by homologous sequencing and monomer model comparison as the key site which was conserved and located around the binding site of the inhibit...

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Detalles Bibliográficos
Autores principales: Han, Caijing, Fang, Li, Liu, Chunlei, Gao, Yunna, Min, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321352/
https://www.ncbi.nlm.nih.gov/pubmed/30572676
http://dx.doi.org/10.3390/molecules23123379