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Construction of Novel Aspartokinase Mutant A380I and Its Characterization by Molecular Dynamics Simulation
In this study, a novel monomer aspartokinase (AK) from Corynebacterium pekinense was identified, and its monomer model was constructed. Site 380 was identified by homologous sequencing and monomer model comparison as the key site which was conserved and located around the binding site of the inhibit...
Autores principales: | Han, Caijing, Fang, Li, Liu, Chunlei, Gao, Yunna, Min, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321352/ https://www.ncbi.nlm.nih.gov/pubmed/30572676 http://dx.doi.org/10.3390/molecules23123379 |
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