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TfOH-Promoted Reaction of 2,4-Diaryl-1,1,1-Trifluorobut-3-yn-2-oles with Arenes: Synthesis of 1,3-Diaryl-1-CF(3)-Indenes and Versatility of the Reaction Mechanisms

The TfOH-mediated reactions of 2,4-diaryl-1,1,1-trifluorobut-3-yn-2-oles (CF(3)-substituted diaryl propargyl alcohols) with arenes in CH(2)Cl(2) afford 1,3-diaryl-1-CF(3)-indenes in yields up to 84%. This new process for synthesis of such CF(3)-indenes is complete at room temperature within one hour...

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Detalles Bibliográficos
Autores principales:	Zerov, Aleksey V., Kazakova, Anna N., Boyarskaya, Irina A., Panikorovskii, Taras L., Suslonov, Vitalii V., Khoroshilova, Olesya V., Vasilyev, Aleksander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321356/ https://www.ncbi.nlm.nih.gov/pubmed/30477271 http://dx.doi.org/10.3390/molecules23123079

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