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Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents

With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a–3l) were synthesized and characterized. Due to thione-thiol tautomerism in the intermediate compound 2, type of substitution reaction in the final step was determ...

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Detalles Bibliográficos
Autores principales: Karaburun, Ahmet Çağrı, Acar Çevik, Ulviye, Osmaniye, Derya, Sağlık, Begüm Nurpelin, Kaya Çavuşoğlu, Betül, Levent, Serkan, Özkay, Yusuf, Koparal, Ali Savaş, Behçet, Mustafa, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321371/
https://www.ncbi.nlm.nih.gov/pubmed/30501053
http://dx.doi.org/10.3390/molecules23123129