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Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity

Opioids are highly effective analgesics that have a serious potential for adverse drug reactions and for development of addiction and tolerance. Since the use of opioids has escalated in recent years, it is increasingly important to understand biological mechanisms that can increase the probability...

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Detalles Bibliográficos
Autores principales: Yang, Junzhi, Reilly, Bianca G., Davis, Thomas P., Ronaldson, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321372/
https://www.ncbi.nlm.nih.gov/pubmed/30340346
http://dx.doi.org/10.3390/pharmaceutics10040192