CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer

CCCTC-binding factor (CTCF) is a conserved transcription factor that performs diverse roles in transcriptional regulation and chromatin architecture. Cancer genome sequencing reveals diverse acquired mutations in CTCF, which we have shown functions as a tumour suppressor gene. While CTCF is essentia...

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Detalles Bibliográficos
Autores principales: Bailey, Charles G, Metierre, Cynthia, Feng, Yue, Baidya, Kinsha, Filippova, Galina N, Loukinov, Dmitri I, Lobanenkov, Victor V, Semaan, Crystal, Rasko, John EJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321389/
https://www.ncbi.nlm.nih.gov/pubmed/30513694
http://dx.doi.org/10.3390/ijms19123832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321389/
https://www.ncbi.nlm.nih.gov/pubmed/30513694
http://dx.doi.org/10.3390/ijms19123832

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