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Combined Use of N-Palmitoyl-Glycine-Histidine Gel and Several Penetration Enhancers on the Skin Permeation and Concentration of Metronidazole

N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a much higher skin concentration was confirmed than wi...

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Detalles Bibliográficos
Autores principales: Dahlizar, Sabrina, Futaki, Mika, Okada, Akie, Yatomi, Chihiro, Todo, Hiroaki, Sugibayashi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321412/
https://www.ncbi.nlm.nih.gov/pubmed/30241371
http://dx.doi.org/10.3390/pharmaceutics10040163