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Combined Use of N-Palmitoyl-Glycine-Histidine Gel and Several Penetration Enhancers on the Skin Permeation and Concentration of Metronidazole
N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a much higher skin concentration was confirmed than wi...
Autores principales: | Dahlizar, Sabrina, Futaki, Mika, Okada, Akie, Yatomi, Chihiro, Todo, Hiroaki, Sugibayashi, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321412/ https://www.ncbi.nlm.nih.gov/pubmed/30241371 http://dx.doi.org/10.3390/pharmaceutics10040163 |
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