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Moisture-Resistant Co-Spray-Dried Netilmicin with l-Leucine as Dry Powder Inhalation for the Treatment of Respiratory Infections

Netilmicin (NTM) is one of the first-line drugs for lower respiratory tract infections (LRTI) therapy, but its nephrotoxicity and ototoxicity caused by intravenous injection restrict its clinical application. Dry powder inhalation (DPI) is a popular local drug delivery system that is introduced as a...

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Detalles Bibliográficos
Autores principales: Cui, Yingtong, Zhang, Xuejuan, Wang, Wen, Huang, Zhengwei, Zhao, Ziyu, Wang, Guanlin, Cai, Shihao, Jing, Hui, Huang, Ying, Pan, Xin, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321429/
https://www.ncbi.nlm.nih.gov/pubmed/30513738
http://dx.doi.org/10.3390/pharmaceutics10040252