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Dissecting Pathogenetic Mechanisms and Therapeutic Strategies in Drosophila Models of Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1), the most common cause of adult-onset muscular dystrophy, is autosomal dominant, multisystemic disease with characteristic symptoms including myotonia, heart defects, cataracts and testicular atrophy. DM1 disease is being successfully modelled in Drosophila allowing t...

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Detalles Bibliográficos
Autores principales: Souidi, Anissa, Zmojdzian, Monika, Jagla, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321436/
https://www.ncbi.nlm.nih.gov/pubmed/30567354
http://dx.doi.org/10.3390/ijms19124104