Dissection of the Structural Features of a Fungicidal Antibody-Derived Peptide

The synthetic peptide T11F (TCRVDHRGLTF), derived from the constant region of human IgM antibodies, proved to exert a significant activity in vitro against yeast strains, including multidrug resistant isolates. Alanine substitution of positively charged residues led to a decrease in candidacidal act...

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Detalles Bibliográficos
Autores principales: Pertinhez, Thelma A., Ciociola, Tecla, Giovati, Laura, Magliani, Walter, Belletti, Silvana, Polonelli, Luciano, Conti, Stefania, Spisni, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321458/
https://www.ncbi.nlm.nih.gov/pubmed/30487461
http://dx.doi.org/10.3390/ijms19123792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321458/
https://www.ncbi.nlm.nih.gov/pubmed/30487461
http://dx.doi.org/10.3390/ijms19123792

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