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Formulation and Characterization of Native and Crosslinked Hyaluronic Acid Microspheres for Dermal Delivery of Sodium Ascorbyl Phosphate: A Comparative Study

The present work evaluates for the first time the use of urea-crosslinked hyaluronic acid (HA-CL), a novel derivative of native hyaluronic acid (HA), to produce microspheres (MS) by emulsification-solvent evaporation, for dermal delivery of sodium ascorbyl phosphate (SAP). As the term of comparison,...

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Detalles Bibliográficos
Autores principales: Fallacara, Arianna, Marchetti, Filippo, Pozzoli, Michele, Citernesi, Ugo Raffaello, Manfredini, Stefano, Vertuani, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321467/
https://www.ncbi.nlm.nih.gov/pubmed/30513791
http://dx.doi.org/10.3390/pharmaceutics10040254