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The Role of Combined Penetration Enhancers in Nasal Microspheres on In Vivo Drug Bioavailability

Microspheres based on both methyl-β-cyclodextrins and chitosan were prepared by spray-drying as nasal formulations of a model polar drug to analyze, firstly, how the composition of the carrier affects drug permeation across synthetic membranes and, secondly, how it induces systemic or brain delivery...

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Detalles Bibliográficos
Autores principales:	Rassu, Giovanna, Ferraro, Luca, Pavan, Barbara, Giunchedi, Paolo, Gavini, Elisabetta, Dalpiaz, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321492/ https://www.ncbi.nlm.nih.gov/pubmed/30373187 http://dx.doi.org/10.3390/pharmaceutics10040206

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