Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi

Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as Trypanosoma cruzi. Here, we performed a virtual screening approach to find candidates t...

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Detalles Bibliográficos
Autores principales: Ochoa, Rodrigo, Rocha-Roa, Cristian, Marín-Villa, Marcel, Robledo, Sara M., Varela-M, Rubén E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321509/
https://www.ncbi.nlm.nih.gov/pubmed/30544836
http://dx.doi.org/10.3390/ijms19123951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321509/
https://www.ncbi.nlm.nih.gov/pubmed/30544836
http://dx.doi.org/10.3390/ijms19123951

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