mRNA-Mediated Duplexes Play Dual Roles in the Regulation of Bidirectional Ribosomal Frameshifting

In contrast to −1 programmed ribosomal frameshifting (PRF) stimulation by an RNA pseudoknot downstream of frameshifting sites, a refolding upstream RNA hairpin juxtaposing the frameshifting sites attenuates −1 PRF in human cells and stimulates +1 frameshifting in yeast. This eukaryotic functional mi...

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Detalles Bibliográficos
Autores principales: Huang, Wan-Ping, Cho, Che-Pei, Chang, Kung-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321510/
https://www.ncbi.nlm.nih.gov/pubmed/30518074
http://dx.doi.org/10.3390/ijms19123867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321510/
https://www.ncbi.nlm.nih.gov/pubmed/30518074
http://dx.doi.org/10.3390/ijms19123867

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