S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells

S5 is a withanolide natural product isolated from Physalis pubescens L. Our previous experimental studies found that it has significant antitumor activity on renal cell carcinoma. In the present study, the anti-melanoma effect of S5 and the related molecular mechanism was first investigated. It was...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Yuqi, Mao, Yiwei, Cao, Shijie, Xia, Guiyang, Zhang, Qiang, Zhang, Hongyang, Qiu, Feng, Kang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321527/
https://www.ncbi.nlm.nih.gov/pubmed/30513793
http://dx.doi.org/10.3390/molecules23123175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321527/
https://www.ncbi.nlm.nih.gov/pubmed/30513793
http://dx.doi.org/10.3390/molecules23123175

Ejemplares similares