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S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells

S5 is a withanolide natural product isolated from Physalis pubescens L. Our previous experimental studies found that it has significant antitumor activity on renal cell carcinoma. In the present study, the anti-melanoma effect of S5 and the related molecular mechanism was first investigated. It was...

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Detalles Bibliográficos
Autores principales:	Fan, Yuqi, Mao, Yiwei, Cao, Shijie, Xia, Guiyang, Zhang, Qiang, Zhang, Hongyang, Qiu, Feng, Kang, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321527/ https://www.ncbi.nlm.nih.gov/pubmed/30513793 http://dx.doi.org/10.3390/molecules23123175

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