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Development of Novel Intramolecular FRET-Based ABC Transporter Biosensors to Identify New Substrates and Modulators

Multidrug resistance protein 1 (MRP1) can efflux a wide variety of molecules including toxic chemicals, drugs, and their derivatives out of cells. Substrates of MRP1 include anti-cancer agents, antibiotics, anti-virals, anti-human immunodeficiency virus (HIV), and many other drugs. To identify novel...

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Detalles Bibliográficos
Autores principales: Osa-Andrews, Bremansu, Tan, Kee W., Sampson, Angelina, Iram, Surtaj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321552/
https://www.ncbi.nlm.nih.gov/pubmed/30322148
http://dx.doi.org/10.3390/pharmaceutics10040186