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Development of Novel Intramolecular FRET-Based ABC Transporter Biosensors to Identify New Substrates and Modulators
Multidrug resistance protein 1 (MRP1) can efflux a wide variety of molecules including toxic chemicals, drugs, and their derivatives out of cells. Substrates of MRP1 include anti-cancer agents, antibiotics, anti-virals, anti-human immunodeficiency virus (HIV), and many other drugs. To identify novel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321552/ https://www.ncbi.nlm.nih.gov/pubmed/30322148 http://dx.doi.org/10.3390/pharmaceutics10040186 |