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Binding Study of the Fluorescent Carbazole Derivative with Human Telomeric G-Quadruplexes

The carbazole ligand 3 was synthesized, characterized and its binding interactions with human telomeric (22HT) G-quadruplex DNA in Na(+) and K(+)-containing buffer were investigated by ultraviolet-visible (UV-Vis) spectrophotometry, fluorescence, circular dichroism (CD) spectroscopy, and DNA melting...

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Detalles Bibliográficos
Autores principales: Głuszyńska, Agata, Juskowiak, Bernard, Rubiś, Błażej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321567/
https://www.ncbi.nlm.nih.gov/pubmed/30513661
http://dx.doi.org/10.3390/molecules23123154