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Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells

An epigenetic component, especially aberrant DNA methylation pattern, has been shown to be frequently involved in sporadic breast cancer development. A growing body of literature demonstrates that combination of agents, i.e. nucleoside analogues with dietary phytochemicals, may provide enhanced ther...

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Detalles Bibliográficos
Autores principales: Lubecka, Katarzyna, Kaufman-Szymczyk, Agnieszka, Cebula-Obrzut, Barbara, Smolewski, Piotr, Szemraj, Janusz, Fabianowska-Majewska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321577/
https://www.ncbi.nlm.nih.gov/pubmed/30544666
http://dx.doi.org/10.3390/ijms19123970